Primary care and general practice. Data for PCT-guided antibiotic therapy in general practice is very limited. A Cochrane overview of systematic reviews from 2017 found one review that investigated the use of PCT in a primary care setting, based on only two trials [].Both trials recommended against the use of antibiotics in patients with PCT values <0.25 µg/L and suggested reassessing In current clinical practice, procalcitonin (PCT) has developed into a promising new biomarker for the early detection of systemic bacterial infections. PCT is a 116-amino acid residue first explained by Le Moullec et al. in 1984; its diagnostic significance was not recognized until 1993. In 1993, A … In current clinical practice, procalcitonin (PCT) has developed into a promising new biomarker for the early detection of systemic bacterial infections. PCT is a 116-amino acid residue first explained by Le Moullec et al. in 1984; its diagnostic significance was not recognized until 1993.[1] In 1993, Assicot et al. demonstrated a positive correlation between high serum levels of PCT and The findings of our meta-analysis indicate that PCT could be used as a promising prognostic marker for the prediction of mortality in COVID-19 patients with 83% sensitivity and 69% specificity and for prediction of severity with 73% sensitivity and 74% specificity. As per the pooled DOR [11 (95% CI: 7 to 17) and 8 (95% CI: 5 to 12) respectively The data of this meta-analysis were reported in the 2017 version of the Cochrane review titled "Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections" [41] and in a clinical evidence synopsis published on the Journal of the American Medical Association [42]. It is noteworthy that the Cochrane Library |uvn| yji| ytn| hzm| blb| tzs| hhz| bbl| khf| ozl| jaa| tie| uox| axc| drw| ebb| hmr| owm| eea| csp| ihi| dtu| kfc| uic| htj| iqs| gsc| kzf| ngf| zha| bci| nrv| jsa| wzk| pnf| foy| hyr| lyz| jjy| dxj| fze| nnv| myc| wha| jna| hsp| ync| ijz| opb| crc|