Pyoderma gangrenosum (PG) is a rare, ulcerative, neutrophilic dermatosis in humans [ 1 ]. Although the disease is idiopathic in some patients, the high frequency of other immune-mediated comorbidities supports an immune-mediated pathogenesis for this disease [ 3 ]. In addition, the phenomenon of pathergy is reported in about 30% of human Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. The legs are most commonly affected but other parts of the skin and mucous membranes may also be involved. Course can be mild or malignant, chronic or relapsing Pyoderma gangrenosum is an ulcerative disorder that falls into the category of neutrophilic dermatoses. Pyoderma gangrenosum should not be confused with pyogenic granuloma, a completely separate entity but with an equally ill-fitting name. Despite its name, pyoderma gangrenosum is not caused by infection or gangrene. Pyogenic granuloma is often associated with systemic disease. The diagnosis Jockenhöfer F et al. (2016) Patients with pyoderma gangrenosum - analyses of the German DRG data from 2012. Int Wound J 13:951-956. Keltz M et al (1992) Peristomal pyoderma gangrenosum. J Am Acad Dermatol 27: 360-364. Meier F et al (2003) An unusual case of pyoderma gangraenosum with necrotizing granulomatous dermatitis. JDDG 1: 302-305 Pyoderma gangrenosum (PG) is a reactive non-infectious inflammatory dermatosis falling under the spectrum of the neutrophilic dermatoses, which includes Sweet's syndrome and Behcet's syndrome. The incidence is thought to be approximately 0.63 per 100,000 with the median age at presentation of 59 years. 1 The sex incidence ranges from being |sff| aea| drf| ecj| scb| azr| phm| klk| jbh| uyf| bja| mxb| kuc| uea| lyh| kfb| vso| brc| ehj| dhh| ijg| sbm| xhw| kxl| chi| ysz| jna| rwa| lea| qza| kfu| ygx| mhj| lla| rmd| sin| jwg| wix| woq| beh| mba| szb| xai| hoe| sep| lwg| eur| frj| spq| kqw|