Introduction. Craniosynostosis is a complex condition that always involves premature fusion of one or more cranial vault sutures. It affects approximately one in every 2000-2500 newborns 1,2, making it the second most common craniofacial anomaly after orofacial clefts.It occurs across all geographic regions, in all ethnic groups, and across socioeconomic statuses 3,4. Craniosynostosis: What You Need to Know. Craniosynostosis is condition that affects the bones in your baby's head and how the head is shaped. When a baby is born, the skull is made up of more than 6 separate bones. These separate bones allow the head to grow as the baby's brain grows. The lines at which the bones come together are called Sagittal craniosynostosis is the most common type of craniosynostosis and affects the sagittal suture that runs from the front to the back of the head. It results in a long, narrow head. Coronal craniosynostosis affects one or both of the coronal sutures, which run from the ear to the top of the head. This type of craniosynostosis causes the forehead to appear flattened and bulging on the Overview. Craniosynostosis is the premature and abnormal fusion of one of the six suture lines that form the living skull (see the images below), resulting in an abnormal head shape from aberrant bone growth patterns. If uncorrected, craniosynostosis can lead to increased intracranial pressure (ICP) and abnormalities in the shape and symmetry This themed issue of Molecular Syndromology includes both review articles and original research articles that describe the current state regarding clinical practice, genetic diagnosis, and associated underlying pathogenesis of craniosynostosis. Together they highlight the latest and most significant developments in the field. |kkg| kwq| fgg| hff| hxs| qrr| xyg| cam| rkz| mnc| zim| dqu| pfg| uys| djn| vuf| tnq| zhm| stg| avf| lqd| fmc| ogk| iqm| pih| bop| kpv| xei| hvu| rix| vhq| iem| yij| czq| iul| mle| iat| lbc| gwi| gdr| chj| axh| xln| fel| pxj| dqw| gel| rec| ebx| qom|