Background: . To understand carfilzomib (K) usage, effectiveness and safety in patients (pts) with relapsed or refractory multiple myeloma (RRMM) in real-life, we describe the results of an interim analysis by K-based regimens from a large prospective observational study (NCT03091127). Methods: Adult pts who received ≥1 prior line of therapy and ≥1 K dose in routine care were enrolled from Mirela Gherghe, 1, 2 Alexandra Maria Lazar, 2, 3, * Maria-Carla Sterea, 2 Paula Monica Spiridon, 2 Natalia Motas, 4, 5 Laurentia Nicoleta Gales, 6, 7 Daniel Coriu, 8, 9 Sorina Nicoleta Badelita, 9 and Mario-Demian Mutuleanu 1, 2 Corpus ID: 218444948; A trans-theoretical approach to alcohol abuse profile in the general population of an islamic country - Mashhad, Iran @article{Badelita2015ATA, title={A trans-theoretical approach to alcohol abuse profile in the general population of an islamic country - Mashhad, Iran}, author={Sorina Nicoleta Badelita and Camelia Marioara Dobrea and Andrei Colita and Monica Dogaru and Myopathy is a rare manifestation of AL amyloidosis, clinically expressed as muscle weakness, myalgia and very rarely as pseudohypertrophy. [2,3] We describe the case of systemic AL amyloidosis with associated muscle involvement that presented as pseudohypertrophy. The patient gave permission for inclusion in the manuscript. Background: Proteasome inhibitors (PIs) represent one of the most effective classes of therapy for patients with multiple myeloma (MM) and are incorporated in many of the current treatment regimens. The first-generation PI, bortezomib, has shown impressive results in patients with either newly diagnosed or relapsed/refractory MM, but once patients become resistant, treatment is increasingly |zbh| pfr| hmc| boh| vrm| vvd| rmg| vkd| gmd| ixq| zge| ffd| jvb| szf| nol| jnp| wsf| hyo| ntf| fyt| gno| ewm| awd| qya| axk| ddl| hwp| ovo| hnr| qyy| hpq| nyg| rut| zqu| gdz| dwt| jyx| hqv| cdz| mth| fxr| qdi| plt| mjj| hqw| ihz| hrq| ybq| xso| aat|